Living with Crohns and Ulcertative Colitis. Personal experience with the chronic disease. Coping mechanisms and life style change. I am not a doctor, and the opinions expressed on this blog should NOT be substituted for the counsel of your doctor.
From our friends at Healthy Holistic Living we present to you the Poop Chart. It is all about color and shape. Based on the chart I am a Type 4 and 5. So I am the ultimate miracle pooper with Crohns and Colitis. Check out their article for more information:
Patients are needed to participate in a clinical research study of GS-5745 and Placebo to evaluate Ulcerative Colitis
RESEARCH STUDY SUMMARY
Patients are needed to participate in a clinical research study of GS-5745 and Placebo to evaluate Ulcerative Colitis
RESEARCH STUDY TITLE
A Phase 1 Double-blind, Randomized, Placebo-Controlled, Staggered, Single and Multiple Ascending Dose, Multicenter Study Evaluating the Safety, Tolerability, Pharmacokinetics and Efficacy of GS-5745 in Subjects With Moderate to Severe Ulcerative Colitis
This is a staggered, placebo-controlled, single and multiple ascending dose (SAD/MAD) study evaluating the safety, tolerability and pharmacokinetics of GS-5745 in patients between ages of 18 to 65 years with moderate to severe ulcerative colitis. This study will provide valuable data that can help establish the safety, pharmacokinetics and efficacy of GS-5745 in ulcerative colitis patients.
For more information click on link below for contact information and locations
Everyone knows stress held in can do damage on the body. If we do not have an outlet, it can work inward. Metaphysical Colitis represents ‘Insecurity. The ease of letting go of that which is over.’ Crohn’s Disease represents ‘Fear. Worry. Not feeling good enough.’ Affirmations: Colitis – ‘I am part of the perfect rhythm and flow of life. All is in Divine right order.’ Crohn’s Disease – ‘I love and approve of myself. I am doing the best I can. I am wonderful. I am at peace.’
The iGenoMed project is looking to better understand how patients living with Inflammatory Bowel Disease (IBD) feel about how treatment decisions are currently made. Please complete the following survey in order to help us better understand how you feel during your consultations with your physician.
Your participation in this research will consist of complete this questionnaire divided into seven sections. Each section will invite you to choose the statement that you feel best describes your situation. Simply check the box that best describes your opinion on a scale of 1 to 6. We hope that you complete the entire questionnaire, but, you may choose not to answer any of the questions and to end the survey at any time. The maximum time required to complete the survey should be approximately 15 minutes.
Of course, your answers will be kept anonymous. Your participation in this project is limited, it will never be possible to identify you. Thus, the data from your responses will be kept for further analysis or other research in anonymous form. It should be noted that since no data that can identify you (eg name, address) is collected through the questionnaire, the data obtained from a participant after the researcher receive the completed questionnaire cannot be destroyed, even if you decide to withdraw from the project.
If you have any questions about this research, or how your answers will be used, please contact the co-investigator responsible of the project, Professor Sophie Veilleux, at Laval University’s Faculty of Business Administration by Email at email@example.com. Please also note that the contribution of the Crohn's and Colitis Foundation of Canada in the research project is this work.
Your cooperation in this study is valuable to us. That is why we would like to thank you for the time and attention that you agree to devote with your participation.
Simply returning the completed questionnaire will be considered the implicit expression of consent to participate. If you have any complaints or criticisms regarding your participation in this research, please contact, in confidence, to the Ombudsman from Laval University at the following address:
Pavillon Alphonse-Desjardins Tel. : (418) 656-3081 University Laval Toll-free number: 1-866-323-2271 2325 University Street, Suite 3320 Quebec (Quebec) G1V 0A6 Email: firstname.lastname@example.org
Let’s face it: most of us don’t get the fiber we need in our diets. It’s true. And we fail to get all the water we need as well. These two things along with improper toilet posture which doesn’t allow us to eliminate completely is a bad combination that creates hard dry stools. These hard dry stools are very hard to push out. It’s called constipation, and we’ve all experienced it. Unfortunately, it’s the norm for altogether too many of us. But that’s just the beginning…
Getting those hard stools out calls for lots of pushing. And that pressure causes hemorrhoids, which can be very painful. Hemorrhoids are inflamed anal varicose veins that have swollen because of our need to push excessively to get those hard stools to pass. And as bad as hemorrhoids are, they aren’t the worst of our potential problems.
#3: Colon Disease
Eliminating completely and often helps maintain good colon health. Many studies point to fecal buildup in the colon as a cause of diseases including colon cancer. And when there is buildup in the colon, our bodies can’t absorb all the nutrients from the food we eat, leaving us without the energy we could enjoy if our colons were healthy.
#4: Urinary Difficulty/Infections
Urinary flow is usually stronger and easier when women squat to urinate. The bladder is emptied more completely when squatting rather than sitting or “hovering”. Squatting can help reduce episodes of urinary tract infections in both frequency and intensity. Now, that is good news!
#5: Pelvic Floor Issues
One of the main causes of this condition is straining on the toilet. The “sitting” position causes a great amount of pressure on the anorectal Angle of the colon causing the lower part of the colon to drop and protrude into the wall of the vagina. Pelvic floor nerves can be protected by squatting for bowel elimination. Men can also suffer from pelvic floor disorders and can readily benefit from using the Squatty Potty as a part of their everyday routine.
WHAT EFFECT DOES SMOKING MARIJUANA HAVE ON CROHN'S DISEASE
Crohn's disease causes symptoms of pain, bloating, diarrhea, constipation, weight loss for some from nutritional deficiencies and can affect any part of the body from the mouth to the intestinal tract. Marijuana is used medicinally to treat a variety of gastrointestinal issues including nausea. Researchers recently studied the role of cannabis (marijuana) to find out if the plant could help treat Crohn's disease.
The group was randomly assigned to either smoke medical marijuana or a 'dummy' (placebo) cigarette for 8-weeks. All of the patients in the study had active Crohn's disease and 80 percent had either not responded to anti-tumor necrosis factor therapy or were unable to tolerate the treatment.
The study authors used inhaled marijuana instead of ingested forms to boost blood levels of THC compounds rapidly.
The researchers found THC, the active component in marijuana decreased Crohn's disease activity in 90 percent of of those treated, compared to just 40 percent of the placebo group. Three patients were able to stop taking steroids, there were no side effects and the study participants given marijuana reported improved appetite and better sleep.
But the effects were temporary. Smoking marijuana also failed to reduce inflammation that is the hallmark of Crohn's disease. Patients relapsed two-weeks after stopping therapy, the study found.
The study authors concluded cannabis should not be recommended for long-term use for Crohn's disease, pending more studies. The investigation was the first double-blind, placebo-controlled study to investigate whether marijuana cannabinoids that have a known anti-inflammatory effect could be beneficial for treating Crohn's disease. There is also concern about marijuana's harmful effect on the lungs. The study authors recommended larger trials that use another form of marijuana other than smoking.
The FDA has approved a new modality, a novel video capsule endoscopy device, to detect colon polyps in patients with incomplete optical colonoscopy in whom a complete evaluation of the colon is not technically possible.
PillCam COLON (Given Imaging Ltd.) received clearance under the direct de novo classification for devices with low to moderate risk that have no predicate on the market, the manufacturer stated in a press release.
The device consists of a small capsule (12 mm x 33 mm), designed to be swallowed, that is equipped with two miniature color video cameras on each end, a battery and an LED light source.
The cameras are able to transmit as many as four to 35 frames per second to a recording device for up to 10 hours. Data can then be transferred from the device to a computer using RAPID software for clinician review.
"We have made tremendous strides in increasing the number of people who are getting screened for colon cancer, starting at age 50 for the average risk individual. Colonoscopy is the most comprehensive option, but for up to 10% of individuals, achieving a complete colonoscopy may not be possible," Eric Hargis, CEO of the Colon Cancer Alliance said in a press release. "For those individuals, PillCam COLON capsule endoscopy could be an effective option to allow their gastroenterologist to complete a colon examination."
PillCam COLON is expected to benefit approximately 750,000 U.S. patients who experience incomplete colonoscopies each year. Those at risk include women, due to higher incidence of past pelvic surgeries and anatomical differences including particularly acute rectosigmoid angles in thin women.
Patients with a redundant or long colon, history of abdominal surgery or advanced diverticular disease are also at a higher risk for experiencing an incomplete colonoscopy.
FDA approval was based on data from a 16-site clinical trial involving 884 patients that assessed the safety and effectiveness of PillCam COLON in detecting adenomas at least six millimeters in size.
Results from this clinical trial demonstrated 88% sensitivity and 82% specificity. A separate analysis of the same data that used a more restrictive methodology indicated the positive percent agreement for PillCam COLON and optical colonoscopy was 69%, and negative percent agreement was 81% for polyps at least six millimeters in size.
PillCam COLON is currently commercially available in more than eighty markets including Japan, Europe, Latin America, Canada, Australia and parts of Asia and Africa.
HOW IMPORTANT IS VITAMIN D FOR TREATING CROHN'S AND
ULCERATIVE COLITIS PATIENTS?
If you suffer from Crohn's disease or ulcerative colitis or other forms of IBD vitamin D could play a role in quelling inflammation, preserving bone health and boosting immunity.
Why might vitamin D be so important for IBD?
The vitamin that is actually a hormone is important for proper immune function and for optimal bone health. Crohn's and ulcerative colitis might lead to bone loss from a combination of factors that include steroid therapy, inability to absorb calcium or poor diet.
Levels that are below normal may even up the risk of developing inflammation and colitis in the first place.
Last year researchers reported findings from two separate investigations showing the link between low levels of vitamin D that they associated with higher rates of hospitalization and surgery related to inflammatory bowel disease.
Ashwin Ananthakrishnan, MD, from Massachusetts General Hospital in Boston said in a press release: "Low plasma 25-hydroxy vitamin D was associated with an increased risk of surgery and hospitalization in inflammatory bowel disease, primarily Crohn's disease."
In animal studies, researchers found administering active forms of vitamin D reduces inflammation.
In their study, researchers also discovered just 40 percent of 3217 patients with Crohn's disease or ulcerative colitis had sufficient vitamin D, highlighting the importance of monitoring.
In a separate study the researchers noted getting adequate vitamin D levels with supplements also correlated with increased muscle strength and improved quality of life for people with Crohn's disease and ulcerative colitis - both of which are top reasons to know your status.
How much vitamin D do you need?
The researchers said study participants reported boosting levels of vitamin D improved their bowel habits and ability to socialize at levels that were at least 75 nmol/L.
The study authors concluded healthcare providers should consider prescribing vitamin D supplements for anyone dealing with IBD. Participants with the lowest levels of the vitamin showed the most significant improvement, the investigators also noted.
If you are dealing with Crohn's disease or ulcerative colitis, check with your doctor to ensure you are maintaining adequate levels of vitamin D that can be measured with a simple blood test.
Correlating with the findings was a 2012 study that showed IBD strikes fewer women in the Southern latitude. The authors speculated it may be from sun exposure that helps the body synthesize vitamin D into its circulating form. More studies are needed to understand how vitamin D could help treat IBD and there remains conflicting data about the benefits. If you are dealing with Crohn's or colitis vitamin D supplementation could be therapeutic for keeping your bones healthy, possibly reducing inflammation to control symptoms and potentially for boosting immune function.
November is Crohn’s and Colitis awareness month, a time when the Crohn’s and Colitis Foundation of Canada asks Canadians to learn about these two most common forms of inflammatory bowel disease (IBD).
Canada has among the highest incidence and prevalence rates of Crohn’s disease and ulcerative colitis in the world, recent studies show that one in 160 Canadians is suffering from IBD. Intestinal health is something we should all be thinking of, one of the ways you may chose to support your intestinal well being is with supplements. – Dr. Elvis, ND
Dr. Saleh Naser is on a mission. For the last 18-years he's dedicated his life to finding a cure for Crohn's disease. The sometimes debilitating bowel ailment affects hundreds of thousands of Americans.
Dr. Saleh and his team at the University of Central Florida say they believe they've found a cure. Their method is in clinical trials right now.
FOX 35's Tom Johnson spent a day in Naser's lab to find out how it works and why the researchers are so confident their work will result in a cure.